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ProductsBack/ERalpha17p

ERalpha17p

HY-P10393

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
ERalpha17p
Delivery Days Customer
5
Certification
Research Use Only
Scientific Description
ERalpha17p (ERalpha 295-311) is the epitope of the CaM binding site on the estrogen receptor alpha (ER), which interacts with calmodulin (CaM) in a calcium-dependent manner. ERalpha17p regulates the migration of cancer cells MCF-7, SK-BR-3, T47D, and MDA-MB-231 through Rho/ROCK and PI3K/Akt signaling pathways. ERalpha17p inhibits proliferations of breast cancer cells, induces apoptosis , and inhibits tumor growth in mouse models [1] [2] [3] .
UNSPSC
12352202