ERCC1 Polyclonal Antibody

Reddot Biotech

ERCC1 Polyclonal Antibody

5

1.1 mg/ml

ERCC1

ERCC excision repair 1, endonuclease non-catalytic subunit

COFS4; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); RAD10; UV20

Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5-incision during DNA repair. It forms a complex with ERCC11,XPF and ERCC4,which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1,together with RRM1,are determinants of survival after surgical treatment of early-stage,non-small-cell lung cancer. (Ref: Simon,ER. 2005)

-20°C

12352203