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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA903141(ERG Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA903141(ERG Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA903141(ERG Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200)

ERG Antibody

CSB-PA903141
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetERG
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Overview

  • Supplier
    Cusabio
  • Product Name
    ERG Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2078
  • Target name
    ERG
  • Target description
    ETS transcription factor ERG
  • Target synonyms
    ERG, ETS transcription factor; erg-3; erythroblast transformation-specific transcription factor ERG variant 10; ets-related; FUS/ERG fusion protein; p55; TMPRSS2/ERG fusion; transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP11308
  • Protein Name
    Transcriptional regulator ERG
  • Scientific Description
    This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewings sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203