ERK2/p38alpha MAPK-IN-1

MedChem Express

ERK2/p38alpha MAPK-IN-1

5

Research Use Only

C20H16FN3O4S2

445.49

ERK2/p38alpha MAPK-IN-1 (Compound 1, In silico Hit-2) is a potent and selective ERK2 and p38alpha MAPK inhibitor, with an IC50 of 82 microM for ERK2. ERK2/p38alpha MAPK-IN-1 binds to the allosteric site of ERK2 and p38alpha MAPK in distinct manners. ERK2/p38alpha MAPK-IN-1 can be used for the research of type 2 diabetes[1].

COC1=C(OC)C=C(N=C(NC(C2=CSC(COC3=CC=C(F)C=C3)=N2)=O)S4)C4=C1

12352200