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ProductsBack/ERLIN2 Antibody, FITC conjugated

ERLIN2 Antibody, FITC conjugated

CSB-PA007791LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetERLIN2
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Overview

  • Supplier
    Cusabio
  • Product Name
    ERLIN2 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID11160
  • Target name
    ERLIN2
  • Target description
    ER lipid raft associated 2
  • Target synonyms
    C8orf2; endoplasmic reticulum lipid raft-associated protein 2; epididymis secretory sperm binding protein; erlin-2; NET32; spastic paraplegia 18 (autosomal dominant); SPFH domain family, member 2; SPFH2; SPG18; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO94905
  • Protein Name
    Erlin-2
  • Scientific Description
    Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203