ESPL1 Polyclonal Antibody
RD76827A
TargetESPL1
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameESPL1 Polyclonal Antibody
- Delivery Days Customer5
- Concentration0.5 mg/ml
- Gene ID9700
- Target nameESPL1
- Target descriptionextra spindle pole bodies like 1, separase
- Target synonymscaspase-like protein ESPL1; ESP1; extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle poles like 1; extra spindle poles-like 1 protein; SEPA; separin; separin, cysteine protease
- Scientific DescriptionStable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
- Storage Instruction-20°C
- UNSPSC12352203