Estrogen Receptor Oe+/-(ER) Monoclonal Antibody

Reddot Biotech

Estrogen Receptor Oe+/-(ER) Monoclonal Antibody

5

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

100 ug/ml

ESR1

estrogen receptor 1

E2 receptor alpha; ER; Era; ER-alpha; ESR; ESRA; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; ESTRR; NR3A1; nuclear receptor subfamily 3 group A member 1; oestrogen receptor alpha

Mouse

Estrogen receptor (ER) is a steroid receptor of nuclear receptor superfamily, which consists of 553 aa. ER have three domains: the central domain of DNA binding, the hormone binding domain of C-terminal and the transcriptional activation domain of N-terminal. ER is involved in the regulation of female sex hormones, mainly mediating the growth, differentiation and other functions of 17 (E2) on several target tissues . ER Oe+/- is expressed in the nucleus of epithelial cells of normal breast and endometrium, and also in breast cancer. Immunohistochemistry analysis showed that the overall survival rate of steroid positive prediction is good. RE Oe+/- can also be used as a tumor marker combined with anti-progesterone receptor antibody.

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