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ProductsBack/ETO / RUNX1T1 antibody - ChIP grade
ChIP analysis of sheared chromatin from 1.25x10? SKNO-1 cells using GTX60332 ETO / RUNX1T1 antibody - ChIP grade. QPCR was performed using primers specific for the FUT7, NFE2, OGG1 and VEGF genes. This figure shows the occupancy, calculated as the ratio + control/background for which the H2B gene was used. Antibody amount : 4microl
ChIP analysis of sheared chromatin from 1.25x10? SKNO-1 cells using GTX60332 ETO / RUNX1T1 antibody - ChIP grade. QPCR was performed using primers specific for the FUT7, NFE2, OGG1 and VEGF genes. This figure shows the occupancy, calculated as the ratio + control/background for which the H2B gene was used. Antibody amount : 4microl
ChIP analysis of sheared chromatin from 1.25x10? SKNO-1 cells using GTX60332 ETO / RUNX1T1 antibody - ChIP grade. QPCR was performed using primers specific for the FUT7, NFE2, OGG1 and VEGF genes. This figure shows the occupancy, calculated as the ratio + control/background for which the H2B gene was used. Antibody amount : 4microl

ETO / RUNX1T1 antibody - ChIP grade

GTX60332
GeneTex
ApplicationsChIP Chromatin ImmunoPrecipitation, ELISA
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetRUNX1T1
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Overview

  • Supplier
    GeneTex
  • Product Name
    ETO / RUNX1T1 antibody - ChIP grade
  • Delivery Days Customer
    9
  • Application Supplier Note
    ELISA: 1:100. ChIP assay: 1-10 microl. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ChIP Chromatin ImmunoPrecipitation, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID862
  • Target name
    RUNX1T1
  • Target description
    RUNX1 partner transcriptional co-repressor 1
  • Target synonyms
    acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; CBFA2T1; CDR; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; eight twenty one protein; ETO; MTG8; myeloid translocation gene on 8q22; protein CBFA2T1; runt related transcription factor 1; translocated to, 1 (cyclin D related); RUNX1 translocation partner 1; zinc finger MYND domain-containing protein 2; ZMYND2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ06455
  • Protein Name
    Protein CBFA2T1
  • Scientific Description
    This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5-region of the runt-related transcription factor 1 gene fused to the 3-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203