ETO / RUNX1T1 antibody - ChIP grade

GeneTex

ETO / RUNX1T1 antibody - ChIP grade

9

ELISA: 1:100. ChIP assay: 1-10 microl. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ChIP Chromatin ImmunoPrecipitation, ELISA

Research Use Only

Polyclonal

Unconjugated

RUNX1T1

RUNX1 partner transcriptional co-repressor 1

AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2, protein CBFA2T1, RUNX1 translocation partner 1, acute myelogenous leukemia 1 translocation 1, cyclin-D related, core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related, eight twenty one protein, myeloid translocation gene on 8q22, runt related transcription factor 1; translocated to, 1 (cyclin D related), zinc finger MYND domain-containing protein 2

Rabbit

IgG

Protein CBFA2T1

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5-region of the runt-related transcription factor 1 gene fused to the 3-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Human

-20°C or -80°C,2°C to 8°C

12352203