Bio-Connect
Chemical Structure
Chemical Structure
Chemical Structure

Etoposide [33419-42-0]

AG-CR1-3572
AdipoGen Life Sciences
CAS Number33419-42-0
Product group Chemicals
Estimated Purity>98%
Molecular Weight588.6
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Etoposide
  • Delivery Days Customer
    10
  • CAS Number
    33419-42-0
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger
  • Molecular Formula
    C29H32O13
  • Molecular Weight
    588.6
  • Scientific Description
    Chemical. CAS: 33419-42-0. Formula: C29H32O13. MW: 588.6. Semisynthetic derivative of podophyllotoxin. Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells - Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines [1, 5]. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication [2, 4, 6]. p53 activator [3]. Blocks the cell cycle between the end of the S phase and the early G2 phase [2, 8]. Oncoprotein Mdm2 synthesis inhibitor [7]. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway [9, 10]. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing) [11, 14, 15]. Chemotherapeutic compound used in cancers [12, 13]. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation [16]. Highly effective in mobilizing stem cells [17]
  • SMILES
    [H][C@]12COC(=O)[C@]1([H])[C@H](C1=CC(OC)=C(O)C(OC)=C1)C1=C(C=C3OCOC3=C1)[C@H]2O[C@]1([H])O[C@]2([H])CO[C@@H](C)O[C@@]2([H])[C@H](O)[C@H]1O
  • Storage Instruction
    RT
  • UNSPSC
    12352200

Related products

Product group Chemicals
Biorbyt
EtoposideORB594555
CAS Number33419-42-0
Molecular Weight274.31
  • SizePrice
Product group Chemicals
AbMole BioScience
CAS Number33419-42-0
Estimated Purity0.998
Molecular Weight588.56
  • SizePrice
Product group Chemicals
MedChem Express
EtoposideHY-13629
CAS Number33419-42-0
Estimated Purity99.94
Molecular Weight588.56
  • SizePrice
Product group Chemicals
Santa Cruz Biotechnology
CAS Number33419-42-0
  • SizePrice
Product group Chemicals
RayBiotech
Etoposide331-10235
  • SizePrice
Product group Chemicals
Abbexa
  • SizePrice
Product group Chemicals
Biosynth
CAS Number33419-42-0
Molecular Weight588.56 g/mol
  • SizePrice
Product group Chemicals
Enzo Life Sciences
EtoposideBML-GR307
  • SizePrice
Etoposide [33419-42-0]
Product group Chemicals
TargetMol Chemicals
CAS Number33419-42-0
Estimated Purity99.95%
Molecular Weight588.56
  • SizePrice