EV-A71-IN-1

TargetMol Chemicals

EV-A71-IN-1

65

2413648-96-9

Chemical

EV-A71-IN-1

C21H15N5S

369.44

EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 uM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 uM) [1].

3 years

N(C1=NC(C=2N3C(=NC2)N=CC=C3)=CS1)C4=CC=C(C=C4)C5=CC=CC=C5

-20°

12352200