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EVA-1/MPZL2 Protein, Human, Recombinant (hFc)

EVA-1/MPZL2 Protein, Human, Recombinant (hFc)

TMPK-00737
TargetMol Chemicals
Molecular Weight41.39 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    EVA-1/MPZL2 Protein, Human, Recombinant (hFc)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    41.39 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
  • Scientific Description
    MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons. EVA-1/MPZL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 41.39 kDa and the accession number is O60487.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse. Wesdorp M et al., 2018 Jul 5, Am J Hum Genet
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