Exarafenib [2639957-39-2]

MedChem Express

Exarafenib [2639957-39-2]

10

2639957-39-2

Research Use Only

99.68

C26H34F3N5O3

521.58

Exarafenib (RAF/KIN_2787) is an orally-available, selective pan-RAF inhibitor. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. Exarafenib has anticancer activity[1][2].

CC1=CC=C(NC(N2C[C@@H](CC2)CC(F)(F)F)=O)C=C1C3=CC(N[C@H](C)CO)=NC(N4CCOCC4)=C3

2°C to 8°C

12352200