Exatecan intermediate 9

MedChem Express

Exatecan intermediate 9

14

Research Use Only

99.80

C26H24FN3O5

477.48

Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 microM)[1].

O=C(OC1)[C@](O)(CC)C2=C1C(N3C(C4=NC5=CC(F)=C(C)C6=C5C(C(NC(C)=O)CC6)=C4C3)=C2)=O

2°C to 8°C

12352200