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(E/Z)-BCI [15982-84-0]

Research Use Only
S0056
Selleck Chemicals
CAS Number15982-84-0
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    (E/Z)-BCI [15982-84-0]
  • Delivery Days Customer
    9
  • CAS Number
    15982-84-0
  • Certification
    Research Use Only
  • Scientific Description
    (E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 muM and 8.0 muM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
  • UNSPSC
    12352200

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