(E/Z)-BCI [15982-84-0]

S0056
CAS Number15982-84-0
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product Name(E/Z)-BCI [15982-84-0]
- Delivery Days Customer9
- CAS Number15982-84-0
- CertificationResearch Use Only
- Scientific Description(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 muM and 8.0 muM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
- UNSPSC12352200