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EZH2-IN-14

Research Use Only
HY-148458
MedChem Express
Molecular Weight541.69
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    EZH2-IN-14
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C31H39N7O2
  • Molecular Weight
    541.69
  • Scientific Description
    EZH2-IN-14 is a selective EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1.
  • SMILES
    O=C(C1=CC(C2=CC=C(N3CCN(C(C)C)CC3)N=C2)=CC4=C1C=NN4C(C)C)NCC5=C(C)C=C(C)NC5=O
  • Storage Instruction
    See Manual
  • UNSPSC
    12352200