Bio-Connect

F2 Polyclonal Antibody

RD265902A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetF2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    F2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2147
  • Target name
    F2
  • Target description
    coagulation factor II, thrombin
  • Target synonyms
    prepro-coagulation factor II; prothrombin; prothrombin B-chain; PT; RPRGL2; THPH1; thrombin factor II
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203