Bio-Connect

F5446

HY-150190
MedChem Express
Estimated Purity99.38
Product group Chemicals
Molecular Weight552.94
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Overview

  • Supplier
    MedChem Express
  • Product Name
    F5446
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    99.38
  • Molecular Formula
    C26H17ClN2O8S
  • Molecular Weight
    552.94
  • Scientific Description
    F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo [1] [2] [3] .
  • SMILES
    O=C(C1=CC(C2=C(C3=O)NC=C2C(OCC4=CC=CC=C4)=O)=C(N1S(=O)(C5=CC=C(C=C5)Cl)=O)C3=O)OC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200