FABP5 Antibody (epidermal)

Biorbyt

FABP5 Antibody (epidermal)

16

Titering of the FABP5 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P, WB

Research Use Only

Monoclonal

CPTC-FABP5-3

Unconjugated

FABP5

fatty acid binding protein 5

EFABP; E-FABP; epidermal-type fatty acid-binding protein; fatty acid binding protein 5 (psoriasis-associated); fatty acid-binding protein 5; KFABP; PAFABP; PA-FABP; psoriasis-associated fatty acid-binding protein homolog

Mouse

IgG2a

Fatty acid-binding protein 5

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

Human

-20°C,2°C to 8°C

12352203