fac-[Re(CO)3(L3)(H2O)][NO3]

TargetMol Chemicals

fac-[Re(CO)3(L3)(H2O)][NO3]

999

Chemical

Research Use Only

fac-[Re(CO)3(L3)(H2O)][NO3]

C25H17N6O8Re

715.64

Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction. It exhibits cytotoxicity against prostate cancer cells, demonstrating an IC50 value of 0.32 microM in PC-3 cells. This compound predominantly localizes to the mitochondria, reducing ATP production and triggering paraptosis in PC3 cells, while not initiating necrosis, apoptosis, or autophagy [1].

3 years

-20°C

12352200