Facinicline (hydrochloride)

MedChem Express

Facinicline (hydrochloride) [677305-02-1]

9

677305-02-1

Research Use Only

99.66

C15H19ClN4O

306.79

Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic alpha7 receptor partial agonist, with a K i of 6 nM for alpha7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT 3 Rs with a K i value of 1.2 nM [1] .

[H]Cl.O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4

2°C to 8°C

12352200