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Factor IX antibody (HRP)

GTX79804
GeneTex
ApplicationsELISA
Product group Antibodies
TargetF9
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Overview

  • Supplier
    GeneTex
  • Product Name
    Factor IX antibody (HRP)
  • Delivery Days Customer
    9
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2 mg/ml
  • Conjugate
    HRP
  • Gene ID14071
  • Target name
    F9
  • Target description
    coagulation factor IX
  • Target synonyms
    Cf-9, Cf9, coagulation factor IX, christmas factor
  • Host
    Sheep
  • Isotype
    IgG
  • Protein IDP16294
  • Protein Name
    Coagulation factor IX
  • Scientific Description
    This gene encodes a vitamin K-dependent serine protease that plays a critical role in the intrinsic pathway of blood coagulation. The encoded protein is an inactive zymogen that is activated by coagulation factor XIa to generate factor IXa, a heterodimer containing heavy and light chains. In association with factor VIII, membrane phospholipids and calcium ions, factor IXa cleaves the inactive zymogen factor X to generate active factor Xa. Genetic deletion of this gene in mice results in a severe bleeding phenotype. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Stephens CJ, Lauron EJ, Kashentseva E, et al. Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9. J Control Release. 2019,298:128-141. doi: 10.1016/j.jconrel.2019.02.009
    Read this paper