FAK (phospho Tyr576) antibody

GeneTex

FAK (phospho Tyr576) antibody

9

Some cross-reactivity with PYK 2 may still be experienced in cases where PYK 2 is overexpressed relative to Focal Adhesion Kinase within the same cell system.

WB: Use at a concentration of 0.1 - 0.5 microg/ml. Predicted molecular weight: 125 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PTK2

protein tyrosine kinase 2

FADK; FADK 1; FAK; FAK1; FAK-related non-kinase polypeptide; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; PTK2 protein tyrosine kinase 2

Rabbit

IgG

Focal adhesion kinase 1

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]

Human, Mouse, Xenopus

-20°C or -80°C,2°C to 8°C

12352203