FAK PROTAC B5 [2471525-44-5]

TargetMol Chemicals

FAK PROTAC B5 [2471525-44-5]

999

Chemical

Research Use Only

FAK PROTAC B5

C41H43ClN10O7

823.3

Compound B5 (FAK PROTAC B5) is a FAK PROTAC degrader exhibiting potent FAK degradation and antiproliferative activities, with an IC50 of 14.9 nM. It also shows excellent plasma stability, moderate membrane permeability, and inhibits cell migration and invasion [1].

3 years

CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(CCCCC(=O)Nc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)ncc1Cl

-20°C

12352200