FAM111B Polyclonal Antibody

Reddot Biotech

FAM111B Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.5 mg/ml

Unconjugated

FAM111B

FAM111 trypsin like peptidase B

cancer-associated nucleoprotein; CANP; family with sequence similarity 111 member B; POIKTMP; serine protease FAM111B

Rabbit

IgG

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

Human

-20°C

12352203