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Famitinib

HY-108713
MedChem Express
CAS Number1044040-56-3
DownloadMSDS
Product group Chemicals
Estimated Purity98.43
Molecular Weight410.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Famitinib [1044040-56-3]
  • Delivery Days Customer
    10
  • CAS Number
    1044040-56-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.43
  • Molecular Formula
    C23H27FN4O2
  • Molecular Weight
    410.48
  • Scientific Description
    Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit , VEGFR-2 and PDGFRbeta with IC 50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively [1] . Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis [2] .
  • SMILES
    O=C1C2=C(NC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2C)CCN1CCN(CC)CC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200