Bio-Connect

FANCI antibody

Research Use Only
ORB66890
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetFANCI
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Overview

  • Supplier
    Biorbyt
  • Product Name
    FANCI antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID55215
  • Target name
    FANCI
  • Target description
    FA complementation group I
  • Target synonyms
    Fanconi anemia complementation group I; Fanconi anemia group I protein; KIAA1794
  • Host
    Rabbit
  • Protein IDQ9NVI1
  • Protein Name
    Fanconi anemia group I protein
  • Scientific Description
    Rabbit polyclonal to FANCI.Fanconi anemia, complementation group I (FANCI) is required for maintenance of chromosomalstability. It plays a role in the repair of DNA double-strand breaks by homologous recombination andin the repair of DNA cross-links. In response to DNA damage it is involved in the S phase and G2phase checkpoints of the cell cycle. FANCI also promotes FANCD2 ubiquitination and recruient toDNA repair sites. Fanconi anemia is a genetically heterogeneous recessive disorder characterized bycytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakageand defective DNA repair.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203