Rofapitide tetraxetan

MedChem Express

FAP-2286

10

Research Use Only

99.54

C67H99N13O18S3

1470.77

Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC 50 value of 2.7 nM for binding to FAP . Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity [1] .

O=C(N1[C@@](C(N[C@@](C(N[C@H](C(N[C@H](C2=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)([H])[C@H](O)C)=O)([H])CCC1)[C@@](CCC4)([H])N4C([C@H](CSCC5=CC(CSCCNC(CN(CCN(CC6)CC(O)=O)CCN(CCN6CC(O)=O)CC(O)=O)=O)=CC(CSC[C@H](N2)C(O)=O)=C5)NC(CCCCC)=O)=O

-20°C

12352200