Western blot analysis of extracts from HepG2, Hela and 293 cells using Fas Antibody.
Western blot analysis of extracts from HepG2, Hela and 293 cells using Fas Antibody.
FAS Antibody
CSB-PA146193
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFAS
Overview
- SupplierCusabio
- Product NameFAS Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID355
- Target nameFAS
- Target descriptionFas cell surface death receptor
- Target synonymsALPS1A; APO-1; APO-1 cell surface antigen; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; Fas (TNF receptor superfamily, member 6); Fas AMA; FAS1; FASLG receptor; FASTM; mutant tumor necrosis receptor superfamily member 6; TNF receptor superfamily member 6; TNFRSF6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily, member 6
- HostRabbit
- IsotypeIgG
- Protein IDP25445
- Protein NameTumor necrosis factor receptor superfamily member 6
- Scientific DescriptionReceptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). Hahne, M. et al. (1995) Int Immunol 7, 1381-6. Nagata, S. (1997) Cell 88, 355-65. Green, D.R. and Ferguson, T.A. (2001) Nat Rev Mol Cell Biol 2, 917-24.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203