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Fasudil (hydrochloride semihydrate)

HY-10341B
MedChem Express
Molecular Weight673.68
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fasudil (hydrochloride semihydrate)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C14H17N3O2S.ClH.1/2H2O
  • Molecular Weight
    673.68
  • Scientific Description
    Fasudil (HA-1077; AT877) hydrochloride semihydrate is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 microM for ROCK1 , IC 50 s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil hydrochloride semihydrate is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3] .
  • SMILES
    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.[H]Cl.[0.5H2O]
  • UNSPSC
    12352200