Fasudil (hydrochloride semihydrate)
HY-10341B
Molecular Weight673.68
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameFasudil (hydrochloride semihydrate)
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC14H17N3O2S.ClH.1/2H2O
- Molecular Weight673.68
- Scientific DescriptionFasudil (HA-1077; AT877) hydrochloride semihydrate is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 microM for ROCK1 , IC 50 s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil hydrochloride semihydrate is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3] .
- SMILESO=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.[H]Cl.[0.5H2O]
- UNSPSC12352200