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Fazirsiran

Research Use Only
HY-132604
MedChem Express
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Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fazirsiran
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    93.86
  • Molecular Formula
    C493H65 F11N163O312P43S6
  • Molecular Weight
    15587.60
  • Scientific Description
    Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes[1]. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
  • SMILES
    [Fazirsiran]
  • Storage Instruction
    -20°C
  • UNSPSC
    41106300