Bio-Connect

FBXO3 Antibody, FITC conjugated

Research Use Only
CSB-PA892132LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetFBXO3
Price on request
Packing Size
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Overview

  • Supplier
    Cusabio
  • Product Name
    FBXO3 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID26273
  • Target name
    FBXO3
  • Target description
    F-box protein 3
  • Target synonyms
    FBA; F-box only protein 3; F-box protein FBX3; FBX3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UK99
  • Protein Name
    F-box only protein 3
  • Scientific Description
    Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203