FBXO3 Antibody, FITC conjugated
CSB-PA892132LC01HU
ReactivityHuman
Product group Antibodies
TargetFBXO3
Overview
- SupplierCusabio
- Product NameFBXO3 Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID26273
- Target nameFBXO3
- Target descriptionF-box protein 3
- Target synonymsFBA; F-box only protein 3; F-box protein FBX3; FBX3
- HostRabbit
- IsotypeIgG
- Protein IDQ9UK99
- Protein NameF-box only protein 3
- Scientific DescriptionSubstrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203