FCGR3A Monoclonal Antibody,PE Conjugated

Cusabio

FCGR3A Monoclonal Antibody,PE Conjugated

20

Flow Cytometry, ImmunoFluorescence, ELISA

Research Use Only

Monoclonal

RPE, Unconjugated

FCGR3A

Fc fragment of IgG receptor IIIa

CD16; CD16A; CD16a antigen; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc gamma receptor III-A; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RIII-alpha; FcgammaRIIIA; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma receptor III-a Fc fragment; neutrophil-specific antigen NA

Mouse

IgG1

Low affinity immunoglobulin gamma Fc region receptor III-A

COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.This clone is cross reactive with non-human primate.1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Stroncek, D.F., et al. (1991) Blood 77:1572.3. Wirthmueller, U., et al. (1992) J. Exp. Med. 175:1381.4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

Human

-20°C or -80°C

12352203