FCN1 Polyclonal Antibody

Reddot Biotech

FCN1 Polyclonal Antibody

5

2 mg/ml

FCN1

ficolin 1

FCNM; ficolin (collagen/fibrinogen domain-containing) 1; ficolin-1; ficolin-A; ficolin-alpha; M-ficolin

Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

-20°C

12352203