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FcRn heavy chain heterodimer antibody [1G3]

GTX14550
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityBovine, Rat
TargetFcgrt
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Overview

  • Supplier
    GeneTex
  • Product Name
    FcRn heavy chain heterodimer antibody [1G3]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1G3
  • Conjugate
    Unconjugated
  • Gene ID29558
  • Target name
    Fcgrt
  • Target description
    Fc fragment of IgG receptor and transporter
  • Target synonyms
    Fc fragment immunoglobulin G receptor; Fc fragment of IgG, receptor, transporter, alpha; Fc receptor, IgG, alpha chain transporter; FcRn; igG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; neonatal Fc receptor
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP13599
  • Protein Name
    IgG receptor FcRn large subunit p51
  • Scientific Description
    binds and transports maternal immunoglobulin gamma from milk; plays a role in providing maternal immunity to neonates [RGD, Feb 2006]
  • Reactivity
    Bovine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Blocking Placental Class G Immunoglobulin Transfer Prevents NMDA Receptor Antibody Effects in Newborn Mice. Garcia-Serra A et al., 2021 Nov, Neurol Neuroimmunol Neuroinflamm
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  • Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells. Deissler HL et al., 2017 Jan, Exp Eye Res
    Read more