Western Blot Positive WB detected in Recombinant protein All lanes: FEN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 37 kDa Observed band size: 45 kDa
Western Blot Positive WB detected in Recombinant protein All lanes: FEN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 37 kDa Observed band size: 45 kDa
FEN1 Antibody
CSB-PA008585LA01DOA
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityPlant
Overview
- SupplierCusabio
- Product NameFEN1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionStructure-specific nuclease with 5\-flap endonuclease and 5\-3\ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5\-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5\-end of a downstream Okazaki fragment. It enters the flap from the 5\-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5\-3\ exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
- ReactivityPlant
- Storage Instruction-20°C or -80°C
- UNSPSC12352203