Fenobam

MedChem Express

Fenobam [57653-26-6]

5

57653-26-6

Research Use Only

99.91

C11H11ClN4O2

266.688

Fenobam is a selective and orally active mGluR5 antagonist ( IC 50 =84 nM) that can penetrate the blood-brain barrier. Fenobam shows the K d values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction [1] [2] [3] .

O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2

-20°C,2°C to 8°C

12352200