FGFR3 antibody [7M13]

GeneTex

FGFR3 antibody [7M13]

9

Neutralisation/Blocking

Research Use Only

Monoclonal

7M13

200 ug/ml

Unconjugated

Fgfr3

fibroblast growth factor receptor 3

CD333; Fgfr-; Fgfr-3; fibroblast growth factor receptor 3; Flg-2; FR3; HBGF; HBGFR; heparin-binding growth factor receptor; Mfr3; sa; sam3

Rat

IgG2

This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]

Mouse

-20°C or -80°C,2°C to 8°C

12352203