FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

TargetMol Chemicals

FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

16

Research Use Only

30.5 kDa (predicted). Due to glycosylation, the protein migrates to 40-55 kDa based on Tris-Bis PAGE result.

Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

-20°C

12352200