Fimasartan

MedChem Express

Fimasartan [247257-48-3]

10

247257-48-3

Research Use Only

98.55

C27H31N7OS

501.65

Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-kappaB and activator protein-1 [1] [2] [3] .

O=C1N(C(CCCC)=NC(C)=C1CC(N(C)C)=S)CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2

-20°C,2°C to 8°C

12352200