Firibastat

MedChem Express

Firibastat [648927-86-0]

10

648927-86-0

Research Use Only

98.0

C8H20N2O6S4

368.51

Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor ( K i =200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats [1] [2] .

O=S(CC[C@H](N)CSSC[C@@H](N)CCS(=O)(O)=O)(O)=O

-20°C,2°C to 8°C

12352200