FL77-24 [2413582-39-3]

TargetMol Chemicals

FL77-24 [2413582-39-3]

16

Research Use Only

C29H24N2O8

528.51

FL77-24, an analog of FL118 and an apoptosis inducer, exhibits antitumor activity with IC50 values of 99.4 nM in HCT116 cells, 118 nM in HepG2 cells, less than 6.4 nM in both MCF-7 and HeLa cells, and 28.5 nM in A549 cells. It primarily induces cell cycle arrest in the S and G2/M phases [1].

O(C)C=1C=C(C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=CC7=C(C6)OCO7)C=C(OC)C1

-20°C

12352200