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Flindokalner

HY-108584
MedChem Express
CAS Number187523-35-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.56
Molecular Weight359.70
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Flindokalner [187523-35-9]
  • Delivery Days Customer
    10
  • CAS Number
    187523-35-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.56
  • Molecular Formula
    C16H10ClF4NO2
  • Molecular Weight
    359.70
  • Scientific Description
    Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels ( K i =3.7 microM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo [1] [2] .
  • SMILES
    O=C1NC2=C(C=CC(C(F)(F)F)=C2)[C@@]1(C3=CC(Cl)=CC=C3OC)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200