Bio-Connect

FLNA Polyclonal Antibody

Research Use Only
RD80160A
Reddot Biotech
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetFLNA
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    FLNA Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence, Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2316
  • Target name
    FLNA
  • Target description
    filamin A
  • Target synonyms
    ABP-280; ABPX; actin binding protein 280; alpha-filamin; CSBS; CVD1; endothelial actin-binding protein; epididymis secretory sperm binding protein; FGS2; filamin A, alpha; filamin-1; filamin-A; FLN; FLN1; FLN-A; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203