FLNA Polyclonal Antibody
RD80160A
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetFLNA
Overview
- SupplierReddot Biotech
- Product NameFLNA Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2316
- Target nameFLNA
- Target descriptionfilamin A
- Target synonymsABP-280; ABPX; actin binding protein 280; alpha-filamin; CSBS; CVD1; endothelial actin-binding protein; epididymis secretory sperm binding protein; FGS2; filamin A, alpha; filamin-1; filamin-A; FLN; FLN1; FLN-A; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203