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AG-44B-0004 | TRAIL-R1 to -R4 Flow Cytometry Pack | AdipoGen Life Sciences available at Bio-Connect | Order online now!

TRAIL-R1 to -R4 Flow Cytomet... | AG-44B-0004 | AdipoGen Life Sciences

TRAIL-R1 to -R4 (human) Flow Cytometry Pack

Set. TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. - TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

ORB429563 | FLOW CYTOMETRY ABSOLUTE COUNT STANDARD | Biorbyt available at Bio-Connect | Order online now!

FLOW CYTOMETRY ABSOLUTE COUNT STANDARD | ORB429563 | Biorbyt

FLOW CYTOMETRY ABSOLUTE COUNT STANDARD

RPE REFERENCE STANDARD Accessory Reagent (OOSA09633) | OOSA09633 | Aviva Systems Biology available at Bio-Connect

RPE REFERENCE STANDARD Accessor... | OOSA09633 | Aviva Systems Biology

RPE REFERENCE STANDARD Accessory Reagent (OOSA09633)

CSR-BRA-FACS1 | Bone Resorption Assay FACS | Cosmo Bio USA available at Bio-Connect | Order online now!

Bone Resorption Assay FACS | CSR-BRA-FACS1 | Cosmo Bio USA

Bone Resorption Assay FACS

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