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Western Blot Positive WB detected in: HL-60 whole cell lysate, MCF-7 whole cell lysate All lanes: FLT3 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 113, 109 kDa Observed band size: 140 kDa
Western Blot Positive WB detected in: HL-60 whole cell lysate, MCF-7 whole cell lysate All lanes: FLT3 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 113, 109 kDa Observed band size: 140 kDa
Western Blot Positive WB detected in: HL-60 whole cell lysate, MCF-7 whole cell lysate All lanes: FLT3 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 113, 109 kDa Observed band size: 140 kDa

FLT3 Antibody

Research Use Only
CSB-PA008733LA01HU
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFLT3
Price on request
Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    FLT3 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2322
  • Target name
    FLT3
  • Target description
    fms related receptor tyrosine kinase 3
  • Target synonyms
    CD135; CD135 antigen; fetal liver kinase 2; FL cytokine receptor; FLK2; FLK-2; fms related tyrosine kinase 3; fms-like tyrosine kinase 3; growth factor receptor tyrosine kinase type III; receptor-type tyrosine-protein kinase FLT3; stem cell tyrosine kinase 1; STK1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP36888
  • Protein Name
    Receptor-type tyrosine-protein kinase FLT3
  • Scientific Description
    Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203