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FLT3 antibody

Research Use Only
ORB66757
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetFlt3
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Overview

  • Supplier
    Biorbyt
  • Product Name
    FLT3 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID14255
  • Target name
    Flt3
  • Target description
    FMS-like tyrosine kinase 3
  • Target synonyms
    B230315G04; CD135; fetal liver kinase 2; FL cytokine receptor; Flk; Flk-; Flk2; Flk-2; Flt-; Flt-3; Ly72; receptor-type tyrosine-protein kinase FLT3; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmf; wmfl
  • Host
    Rabbit
  • Protein IDQ00342
  • Protein Name
    Receptor-type tyrosine-protein kinase FLT3
  • Scientific Description
    Rabbit polyclonal to FLT3.FMS-related tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that regulates hematopoiesis.Upon ligand binding, the receptor is activated inducing a homodimer formation in the plasmamembrane leading to autophosphorylation of the receptor. Activated FLT3 can also phosphorylateand activate multiple cytoplasmic effector molecules in pathways implicated in apoptosis, proliferationand differentiation of hematopoietic cells in bone marrow. Mutations that result in constitutiveactivation of this receptor are associated with acute myeloid leukemia and acute lymphoblasticleukemia.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203