FLT3/CDKs ligand-1 [2452019-67-7]

TargetMol Chemicals

FLT3/CDKs ligand-1 [2452019-67-7]

9

Research Use Only

C26H31N9O3

517.58

FLT3/CDKs ligand-1 (Compound 14) functions as a ligand for target proteins, promoting the degradation of Cyclin-Dependent Kinases (CDK) and FMS-like tyrosine kinase 3 (FLT3), thereby inhibiting the proliferation and survival of leukemia cells associated with FLT3/CDK. This compound is also used in the synthesis of PROTAC FLT3/CDKs Degrader-1.

O=C(OC(C)(C)C)N1CCN(CC2=CC=C(C=C2)NC(=O)C3=NNC=C3NC=4N=CN=C5NC=CC54)CC1

-20°C

12352200