Flumatinib-d3

MedChem Express

Flumatinib-d3

10

Research Use Only

99.9

C29H26D3F3N8O

565.61

Flumatinib-d3 is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRbeta and c-Kit with IC50s of 1.2 nM, 307.6 nM and 665.5 nM, respectively[1].

O=C(NC1=CC(NC2=NC=CC(C3=CC=CN=C3)=N2)=C(C)N=C1)C4=CC=C(CN5CCN(C([2H])([2H])[2H])CC5)C(C(F)(F)F)=C4

-20°C

12131703