FM-381 [2226521-65-7]
HY-102046
CAS Number2226521-65-7
Product group Chemicals
Estimated Purity99.58
Molecular Weight428.49
Overview
- SupplierMedChem Express
- Product NameFM-381 [2226521-65-7]
- Delivery Days Customer10
- CAS Number2226521-65-7
- CertificationResearch Use Only
- Estimated Purity99.58
- Molecular FormulaC24H24N6O2
- Molecular Weight428.49
- Scientific DescriptionFM-381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.
- SMILESCN(C(/C(C#N)=C/C1=CC=C(C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5)O1)=O)C
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200