FMOD Polyclonal Antibody

Reddot Biotech

FMOD Polyclonal Antibody

5

Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

FMOD

fibromodulin

collagen-binding 59 kDa protein; epididymis secretory sperm binding protein; fibromodulin; FM; keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; SLRR2E

Rabbit

IgG

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Human, Mouse, Rat

-20°C

12352203